s and most effectively serve the needs of patients Develops and leverages high level relationships with patient advocacy groups at state and local levels to achieve Vertex goals, bring value to patients , and enhance the company's standing and reputation Serves as a liaison between the patient community and Vertex Collaborates with and facilitates advocacy coalitions for s

The Legal Senior Counsel provides solutions oriented legal advice and support to assigned business functions on a broad array of strategic and tactical matters within a highly regulated environment.The Legal Senior Counsel demonstrates a high degree of autonomy representing significant risk and complexity, working closely with senior company leaders. This is a hybrid role

The Manufacturing Operations Senior Specialist role supports clinical manufacturing of cell and gene therapy operations. This role works with clinical manufacturing team through all phases up to and including commercialization, as well as supporting all aspects of manufacturing such as change controls, risk assessments, deviations and ownership of GMP documentation. Addit

Vertex is seeking a talented individual to join the Engineering and Materials Science group in Boston, MA. The successful candidate will be a highly productive, results oriented individual, able to multi task and generate and implement original ideas that contribute to the successful development and scale up of drug substance processes, including crystallizations, using a

Represent AS&T on cross functional CMC teams to influence late stage product development for commercialization while building strong relationships with key stakeholders. Responsible for method transfers, validation, or co validation to support late phase and commercial projects to various CMOs or between internal groups Own/Review/Approve commercial documents to support n

Vertex currently operates at the forefront of rare disease scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF) and Sickle Cell Disease. In addition to clinical development programs in CF, Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious

The Quality Control Senior Associate role provides a variety of analytical functions that occur in the Quality Control (QC) department supporting validation, testing and reporting of in process, release and stability samples. This role also helps ensure activities occur in an efficient and cGMP compliant manner while fostering the Vertex vision and values. The schedule fo

As a member of the DTE Global Clinical Operations (GCO) team, the Technology Associate Director Clinical Development & Clinical Operations will be a key resource in ensuring the strategy, planning and delivery of key commercial off the shelf (COTS) and a wide range of custom solutions in support of our Clinical Business Partners. The incumbent will partner with DTE and bu

The Associate Director is responsible for managing the operations of Vertex's external commercial network of Drug Product Intermediate manufacturing, working in the External Manufacturing Operations team. Managing the external manufacturing network is a critical component of the Commercial Manufacturing and Supply Chain team's role in ensuring that the company effectively

Lead the tactical execution of design planning, informing the development of scalable, effective distribution strategies to serve short and long term expectations while considering financial impacts and patient/customer experience Collaborate and drive alignment across key stakeholders on distribution and channel strategy development; apply subject matter expertise to max

The individual in this role will support the delivery of the patient and caregiver marketing strategy and tactical plan for our first genetic therapy for hemoglobinothapies (sickle cell disease and beta thalassemia), Casgevy. The Senior Marketing Manager will be responsible for overseeing development of brand and unbranded marketing tactics for the Sickle Cell disease ind

The Senior Director, Quality is responsible for the oversight of Product Quality Leads for all Vertex Small Molecule programs, development and commercial. As the group leader, the Sr. Director is responsible for supporting commercialization, filing/approval, launch, and post approval lifecycle management. This role will partner closely with Quality and business stakeholde

Lead and ensure successful development and implementation of the commercialization (midterm) and portfolio (long term) strategies including brand development, competitive strategy, go to market/launch, and lifecycle decisions for future launches. Execute in close partnership with the Regions, Market Access, Regulatory and Commercial Manufacturing. Deliver foundational ins

Vertex has established a new research site in Boston Seaport where research, development, and clinical manufacturing for cell and genetic therapies will be primarily based Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat and even cure several of the diseases Vertex is focused on, including sickle cell disease, Du

Leads the development of regulatory strategy for multiple and/or complex projects in development (from first in human to post marketing application stage) outlined in Global Regulatory Strategy Documents including for regulatory submission documents and Health Authority communications Represents GRA on core development teams, project teams, and collaborate with regional l